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. Author manuscript; available in PMC: 2013 Dec 7.
Published in final edited form as: Phys Rev Lett. 2013 Oct 10;111(15):158102. doi: 10.1103/PhysRevLett.111.158102
Parameter Description Value Justification
ka Unitless base activation rate 0.01 [51] Order-of-magnitude from [38]
kb Overall activation rate 10 s–1 Order-of-magnitude from [38]
kc Deactivation rate 10 s–1 Order-of-magnitude from [38]
Ka Positive feedback threshold for actin promoter concentration 1 μm –2 Order-of-magnitude from [38]
Da Actin promoter diffusion coefficient 0.8 μm 2/s Typical membrane-bound protein diffusion coefficient [52]
Dm0
Myosin diffusion coefficient at zero actin concentration 2 μm 2/s Chosen in [12]
KD Myosin diffusion threshold, Dm=Dm0/(1+ρa/KD) 0.5 μm –2[53] Chosen in [12]
Natot
Total amount of actin promoter 485* [54] Roughly rescaled by cell size from value chosen in [12] proportional to cell area
ρm0
Initial density of myosin 0.3 μm –2 Chosen such that myosin stress corresponds to that estimated in [14]