Table 1. Summary of the levels (ng/ml) of CXCR2 ligands GRO-α, IL-8 and ENA-78 in CM of BSMC from non-asthmatic (NA) and asthmatic (A) patients (n = 6 per group) after 24 h and 72 h culture under resting (serum-free) and normal growth (presence of 5% FCS) conditions.
| FCS (5%) | 24 hours | 72 hours | |||||
|---|---|---|---|---|---|---|---|
| NA | A | p-value | NA | A | p-value | ||
| GRO-α | - | 0.49 ± 0.30 | 0.60 ± 0.26 | 0.370 | 2.54 ± 1.66 | 3.50 ± 0.87 | 0.002 |
| + | 2.24 ± 1.00 | 5.68 ± 2.00 | >0.0001 | 4.40 ± 2.01 | 10.10 ± 3.23 | 0.022 | |
| IL-8 | - | 1.27 ± 0.47 | 1.69 ± 1.02 | 0.750 | 1.51 ± 0.51 | 5.82 ± 3.53 | 0.026 |
| + | 3.80 ± 1.22 | 9.67 ± 2.05 | 0.002 | 5.23 ± 1.34 | 12.42 ± 2.08 | 0.002 | |
| ENA-78 | - | 0.11 ± 0.04 | 0.07 ± 0.03 | 0.625 | 0.23 ± 0.16 | 0.32 ± 0.12 | 0.016 |
| + | 0.42 ± 0.23 | 0.89 ± 0.33 | 0.021 | 1.00 ± 0.60 | 1.62 ± 0.72 | 0.023 |
p-values were calculated using Mann Whitney U test.