Table 1. FTS and kinase assay data of hits from the ScreenWell kinase inhibitor library.
| Compound | ΔTm at 10 µM (°C) | IC50-JNK1 ( µM) | IC50-p38 ( µM) |
| Staurosporine | 10.03±0.05 | 0.6 (0.4 to 1) | 0.2 (0.1 to 0.4) |
| SP600125 | 6.4±0.06 | 0.7 (0.3 to 1) | 0.4 (0.3 to 0.6) |
| 5-iodotubercidin | 4.29±0.07 | 2.8 (1.2 to 6.3) | 0.2 (0.2 to 0.3) |
| Apigenin | 2.8±0.23 | 20.1 (12.6 to 32.2) | 15.9 (10.8 to 23.5) |
| Quercetin | 2.75±0.22 | 1.7 (1 to 2.8) | 2.0 (1.4 to 3.0) |
| PP1 | 2.55±0.03 | 16.9 (9.9 to 28.8) | 13.8 (5.7 to 33.3) |
| PP2 | 2.33±0.04 | 22.3 (11 to 45.2) | 39.9 (13.2 to 121) |
| AG825 | 2.26±0.15 | 25.0 (11.5 to 54.6) | 28.5 (15.8 to 51.6) |
Data shown as Mean ± SD with n = 3 for ΔTm. IC50 values are Mean (95% confidence intervals) calculated by fitting data averaged from replicates performed twice at separate times.