Table 2. FTS and kinase assay data of hits from the Spectrum Collection.

Compound	ΔTm at 10 µM (°C)	IC50-p38 ( µM)
Geraldol	4.1±0.1	0.8 (0.5 to 1.2)
2′,4′-dihydroxychalcone	3.67±0.50	16.9 (6.8 to 42.1)
Alizarin	3.55±0.65	0.9 (0.6 to 1.4)
2′,3-dihydroxy-4,4′,6-trimethoxychalcone	2.70±0.35	21.5 (11.2 to 41)
Phloretin	2.69±0.33	12.3 (9.6 to 15.8)
3,7-dihydroxyflavone	2.55±0.20	0.8 (0.4 to 1.4)
Chrysin	1.78±0.42	10.1 (6 to 17.1)

Data shown as Mean ± SD with n = 3 for ΔTm. IC₅₀ values are Mean (95% confidence intervals) calculated by fitting data averaged from replicates performed twice at separate times.