Fig. 2.

Endogenous Lumican has anti-angiogenic activity. PanO2 tumor isolates from mice were sectioned, fixed, and stained with anti-CD-31 antibody to detect microvascular density in tumors. Shown are representative immunostaining results from a single experiment that was performed three times in its entirety. CD-31 staining was quantified by densitometry with Image J software and is depicted as the fold increase compared to control mice. Each data point represents the mean ± SE of three independent experiments. * indicate P < 0.05, Student T-test