Foot rot severity was assessed after 0, 20, 28, 40, and 60 wk of Se supplementation in ewes receiving no Se treatment, Na-selenate at a dosage rate of 8.95 mg Se/wk per ewe, or Na-selenite and Se-Yeast at 4.9, 14.7, or 24.5 mg Se/wk per ewe for 62 wk. If a sheep had one foot with a score of 4, or one foot with a score of 3 and a second foot with a score of 2 or greater, or if all 4 feet had FR, then 20 mg/kg oxytetracycline was administered subcutaneously (Liquamycin LA-200; Pfizer Animal Health, Exton, PA) at the 28- and 40-wk foot trimming sessions. No significant differences in parental oxytetracycline treatment were observed for individual treatment groups at 28 wk; however; more ewes with supranutritional Na-selenite treatment were treated with oxytetracyline than ewes receiving the lowest Na-selenite dosage (P = 0.05). At 40 wk, more ewes receiving Na-selenite at the highest dosage had to be treated with oxytetracycline than ewes receiving no Se, Na-selenite at both lower dosages, or Se-yeast at 14.5 mg/wk (all P ≤ 0.05).