Figure 8. Two-dimensional gel maps of the cell lysates of macrophages.

(A) Proteome analysis of wild-type and CatE ^−/− macrophages revealed that almost all the spots located in the areas under pI 6.0–6.7 were identified annexin A₁, and those under pI 6.0–6.5 were identified the oxidized and reduced forms of peroxiredoxin-6 respectively. These data indicate the representative 2-D gel maps of 3 independent experiments. (B) Proteomic analysis with wild-type macrophages treated with H₂O₂ or untreated.