Table 3.
Estimated mean change in day‑3 FSH (IU/L) by urinary paraben concentration tertile from linear regression models.
| Paraben concentration (μg/L) | n | Estimated mean change in FSH (95% CI)a | p-Value |
|---|---|---|---|
| MP | |||
| Tertile 3 (432–2,428) | 37 | 0.35 (–1.07, 1.77) | 0.63 |
| Tertile 2 (154–430) | 37 | 1.04 (–0.39, 2.46) | 0.15 |
| Tertile 1 (10.8–144) | 36 | 0 (Reference) | |
| ptrend | 0.64 | ||
| PP | |||
| Tertile 3 (87.8–727) | 37 | 1.02 (–0.40, 2.43) | 0.16 |
| Tertile 2 (32.0–80.9) | 37 | 1.16 (–0.26, 2.57) | 0.11 |
| Tertile 1 (0.46–29.4) | 36 | 0 (Reference) | |
| ptrend | 0.16 | ||
| BP | |||
| Tertile 3 (6.00–177) | 37 | 0.39 (–1.03, 1.82) | 0.59 |
| Tertile 2 (0.96–5.61) | 37 | 0.95 (–0.48, 2.39) | 0.19 |
| Tertile 1 (< LOD–0.85) | 36 | 0 (Reference) | |
| ptrend | 0.60 | ||
| All model results were adjusted for age; paraben concentrations were SG-corrected. LODs were 1.0 μg/L for MP and 0.2 μg/L for PP and BP. aParameter estimates can be interpreted as an IU/L change in day-3 FSH for each tertile of urinary paraben concentration relative to tertile 1 (reference). For example, in tertile 3 of the PP urinary concentrations, there is a 1.02-IU/L increase, on average, in day-3 FSH compared with tertile 1. | |||