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. Author manuscript; available in PMC: 2013 Dec 7.
Published in final edited form as: Pediatr Hematol Oncol. 2012 Sep 20;29(8):10.3109/08880018.2012.722747. doi: 10.3109/08880018.2012.722747

Table 3.

Log-linear results for the association between maternal xenobiotic detoxification genotypes and childhood medulloblastoma

Gene RefSNP RR1 (95% CI) P-value2 Q-value3
EPHX1 rs1051740 3.26 (1.12, 9.53) 0.010 0.130
GSTA4 rs316133 1.59 (0.59, 4.26) 0.341 0.989
GSTM4 rs1010167 0.68 (0.27, 1.68) 0.390 0.989
CYP1B1 rs1056836 0.70 (0.26, 1.92) 0.480 0.989
EPHX1 rs2234922 1.65 (0.40, 6.80) 0.484 0.989
GSTP1 rs1695 1.96 (0.19, 20.72) 0.566 0.989
CYP2E1 rs2249695 0.77 (0.24, 2.50) 0.667 0.989
NAT2 rs1799930 1.16 (0.52, 2.57) 0.722 0.989
CYP1A1 rs4646903 0.92 (0.29, 2.90) 0.886 0.989
GSTA4 rs3756980 1.07 (0.39, 2.96) 0.891 0.989
NAT2 rs1799929 0.92 (0.25, 3.40) 0.901 0.989
GSTM3 rs1571858 0.97 (0.21, 4.47) 0.966 0.989
CYP1B1 rs1800440 0.99 (0.33, 2.96) 0.989 0.989
1

RR represents the increase or decrease in risk with each additional copy of the minor allele

2

Based on the likelihood ratio test comparing the model that included terms for both offspring and maternal genotypes, to reduced models that included terms for only the offspring or only the maternal genotype

3

False discovery rate adjusted P-value