Figure 5. MazG is required for Mtb survival in vivo and the corresponding lung pathogenesis.

A to B, Bacterial loads in spleen (A) and lung (B) of mice infected with wild-type Mtb (wt), the mazG-null mutant (ΔmazG) and the complemented mutant (compl). Data shown are mean ± S.E from 4 mice per group. (C) Lung sections taken from mice at 8-wk after infection and stained with hematoxylin and eosin. Inserted column shows mean ± S.E of lung inflammation of each group.