Table 1. Relationships between patient characteristics and MUC2 expression levels *.
| Characteristics | Low MUC2 expression group (n=79) | High MUC2 expression group (n=23) | p value † |
|---|---|---|---|
| Demographics: | |||
| Age (years) | 59.2±6.1 | 59.8±6.7 | 0.680 |
| Gravidity | 4.2±1.2 | 3.6±1.2 | 0.107 |
| Parity | 1.1±0.4 | 1.2±0.5 | 0.544 |
| BMI | 23.2±2.6 | 23.0±1.9 | 0.769 |
| Oral contraceptive use >6 months | 7(8.9) | 2(8.7) | 0.980 |
| Smoking >6 months | 12(15.2) | 5(21.7) | 0.458 |
| Alcohol abuse >6 months | 1(1.3) | 1(4.3) | 0.348 |
| Clinical features: | |||
| Ascites | 20(25.3) | 7(30.4) | 0.624 |
| Peritoneal metastasis (including intestinal, bladder and liver metastasis and peritoneal lavage cytological test +) | 62(78.5) | 16(69.5) | 0.375 |
| Lymph node metastasis | 30(38.0) | 8(34.8) | 0.781 |
| Drug resistance during the primary chemotherapeutic course | 2(2.5) | 1(4.3) | 0.650 |
| Pathology: | |||
| Stage ** | 0.383 | ||
| II | 23(29.1) | 4(17.4) | |
| III | 53(67.1) | 17(73.9) | |
| IV | 3(3.8) | 2(8.7) | |
| Histotype | 0.002 § | ||
| Serous | 57(72.2) | 10(43.5) | |
| Mucinous | 7(8.9) | 10(43.5) | |
| Endometrioid | 8(10.1) | 1(4.3) | |
| Clear cell | 5(6.3) | 2(8.7) | |
| Undifferentiated | 2(2.5) | 0(0) | |
| Grade ** | 0.182 | ||
| G1 | 40(50.6) | 8(34.8) | |
| G2 | 19(24.1) | 10(43.5) | |
| G3 | 20(25.3) | 5(21.7) |
* Data are presented as the mean values±standard deviation or as the number (percentage)
** See reference 22
† A two-tailed Student’s t-test or χ2 test was used, as appropriate.
§ Statistical significance.