Table 1. Immunisation with MOG and MSRV-Env-SU induces dose-dependent EAE-like symptoms in C57BL/6 mice.
Group Treatment | disease | mean disease | mean score | max score | mean cumulative |
incidence (nb) | onset (d) | d30 | score d30 | ||
IFA | 0/4 | - | 0 | 0 | 0 |
CFA | 5/5 | 12,2 | 1,4 | 1,8 | 31,2 |
ENV 50 µg | 7/7 | 9,1 | 1,9 | 2,9 | 56,9 |
ENV 10 µg | 7/7 | 14,6 | 0,4 | 1,6 | 18,7 |
Data correspond to those illustrated in figure 4A. Disease incidence, mean time to disease onset, mean clinical score at day 30, mean maximum score and mean cumulative score at day 30 were calculated for each group of mice.