Table 2. Statistical Analysis of EAE-like symptoms after Immunisation with MOG and MSRV-Env complete in C57BL/6 mice.
Group Treatment | Day of Onset +/− SD | p value Time to onset | MMS +/− SD | p value MMS | % body weight at end of experiment +/− SD | p value body weight | Died during study |
No Env | 37.0+/−7.1 | 0.92+/−1.24 | 120.1+/−8.3 | 0/6 | |||
Env 20 µg | 31.7+/−4.0 | 0,0078* | 2.25+/−0.94 | 0,0581 | 110.2+/−8.5 | 0,0339* | 0/6 |
Env 50 µg | 29.2+/−3.6 | 0,0198* | 2.92+/−1.69 | 0,0398* | 101.7+/−18.9 | 0,0323* | 1/6 |
Data correspond to those illustrated in figure 4C. Time to onset was compared using Wilcoxon's survival test; MMSs were compared using Wilcoxon's non-parametric test; Change in body weight at the end of the study was compared using Student's t-test.
* Statistically significant value.