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. 2013 Dec 6;8(12):e80337. doi: 10.1371/journal.pone.0080337

Figure 4. Forrest plot of odds ratios (ORs) for the association of HIF-1α expression with clinicopathological features.

Figure 4

A. ORs with corresponding 95% CIs of the HIF-1α expression with Dukes' stages. OR<1 suggested that unfavorable parameters for the group with increased HIF-1α expression/negative. Overexpressed HIF-1α was associated with advanced Dukes' stage of CRC. B. ORs with corresponding 95% CIs of the HIF-1α overexpression with UICC stage. OR<1 suggested that unfavorable parameters for the group with increased HIF-1α expression/negative and HIF-1α overexpression was associated with advanced stage of CRC. C. ORs with corresponding 95% CIs of the HIF-1α overexpression with depth of invasion. D. ORs with corresponding 95% CIs of the HIF-1α overexpression with lymphnode metastasis.