. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Int J Cardiol. 2013 Feb 8;168(2):10.1016/j.ijcard.2012.12.103. doi: 10.1016/j.ijcard.2012.12.103

Table 3.

Multivariable Cox analysis of risk function for fatal and nonfatal cardiovascular events in 6604 hypertensive patients not taking beta-blockers during the follow-up.

Variable	Hazard ratio (95% CI)	p-value
Night-time heart rate (per 10-beat/min increase)	1.15 (1.05–1.25)	.0069
Male sex	1.68 (1.38–2.03)	<.001
Age (per 10-year increase)	1.71 (1.61–1.81)	<.001
Smoking (yes/no^*)	1.64 (1.34–2.00)	<.001
Diabetes mellitus (yes/no^*)	1.30 (1.02–1.66)	.03
Night-time systolic BP (per 10-mm Hg increase)	1.27 (1.22–1.32)	<.001
Total cholesterol (per 10-mg/dL increase)	1.04 (1.02–1.06)	<.001
Serum creatinine (per 0.1-mg/dL increase)	1.08 (1.05–1.11)	<.001

reference category;

BP indicates blood pressure; alcohol use, body mass index, and diastolic blood pressure were not accepted by the model (p>0.46).