Madden 2013 | |
Methods | Observational, cohort study; non-probability sample. Purpose: learn whether women who use progestin-only methods will experience weight change compared to women using the non- hormonal copper IUD. Primary hypothesis: users of DMPA will gain excess weight and increase their BMI above the copper-IUD users. Secondarily, compare users’ data in LNG-IUD and ENG implant groups to copper-IUD group. |
Participants | 427 women Inclusion criteria: enrolled in CHOICE between the age 18 and 45 years and consented to future studies; chose levonorgestrel-releasing IUD, copper IUD, implant, or DMPA as CHOICE baseline method; baseline height and weight data collected from on-campus enrollment site; able to return to on-campus enrollment site for study activities. Exclusion criteria: recent history of DMPA use before starting baseline CHOICE method; used current method < 11 months or > 12 months and 3 weeks. |
Interventions | DMPA, LNG-IUD, copper-T IUD, or implant. |
Outcomes | Weight change by 12 months |
Notes | After the updated review was submitted, the investigator communicated that an article was accepted for publication. Those results will be add to the next update. Note: Reportedly, the adjusted model indicated no significant difference between the study arms in weight gain. |