Figure 3. FA inhibits LPS-induced.

NF-κB activation in mouse placenta. All pregnant mice were i.p. injected with LPS (300 μg/kg) on GD15. In LPS+FA groups, the pregnant mice were orally administered with 3 mg/kg of FA 1 h before LPS injection. Placentas were collected 2 h after LPS injection. The phosphorylation of IκB and nuclear NF-κB p65 was determined by immunoblot. (A) Placental p-IκB. (B) Nuclear NF-κB p65 in placentas. All experiments were repeated for three times. All data were presented as means ± S.E.M. (control n=3, FA n=3, LPS n=6, LPS+FA n=6) ** P < 0.01 VS the control. ‡‡ P < 0.01 VS LPS group.