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. 2013 Dec 6;8(12):e82825. doi: 10.1371/journal.pone.0082825

Figure 3. Overview of HFD-induced liver gene transcription changes identified by GSEA in C57BL/6J and BALB/c mice.

Figure 3

Only KEGG biological pathways significantly upregulated (red) or downregulated (green) by HFD in at least one of the two strains are reported. The (absolute) Normalised Enrichment Score (NES) computed by GSEA is plotted (with larger values indicative of significant enrichment). FDR q-values (<0.05) were used to identify statistically significant effects of fat feeding on the pathways in C57BL/6J (*) and BALB/c ($).Genes contributing to pathway enrichment are listed in Table 1.