Table 1. Physical exam, clinical chemistry, and biochemical marker parameters can identify live marmosets with bone and/or GI disease.
| Test | Sensitivity | Specificity | PPV | NPV | P value | |
| Combined Disease (BGS) vs No Disease | Serum Albumin < 3.5 g/dL | 90% | 100% | 100% | 67% | 0.046 |
| Body Weight < 325 g | 87% | 100% | 100% | 75% | 0.00050 | |
| Serum Albumin < 3.5 g/dL or body weight < 325 g | 100% | 100% | 100% | 100% | 0.036 | |
| Weight loss > 0.05% peak weight per day | 100% | 100% | 100% | 100% | 0.018 | |
| Bone Disease vs No Bone Disease | Serum Albumin < 3.5 g/dL | 83% | 100% | 100% | 75% | 0.0015 |
| Body Weight < 325 g | 81% | 60% | 68% | 75% | 0.029 | |
| Serum Albumin < 3.5 g/dL or body weight < 325 g | 86% | 67% | 86% | 67% | 0.18 | |
| Weight loss > 0.05% peak weight per day | 100% | 83% | 75% | 100% | 0.048 | |
| BRF < 0.5 | 83% | 100% | 100% | 80% | 0.048 | |
| PTH > 600 pg/mL | 75% | 100% | 100% | 73% | 0.0014 | |
| GI Disease vs No GI Disease | Serum Albumin < 3.5 g/dL | 70% | 75% | 88% | 50% | 0.044 |
| Body Weight < 325 g | 75% | 93% | 96% | 59% | < 0.00010 | |
| Serum Albumin < 3.5 g/dL or body weight < 325 g | 92% | 100% | 100% | 80% | 0.0027 | |
| Weight loss > 0.05% peak weight per day | 100% | 100% | 100% | 100% | 0.0079 |
= positive predictive value, NPV = negative predictive value, BRF = bone radiodensity frequency, PTH = parathyroid hormone. PPV
P values calculated by Fisher’s exact test.
Italicized P values denote non-significant values (P ≥ 0.5).