Table 3. Frequency of ATM protein expression in subgroups according to microsatellite instability (MSI) status and ATM intron mutation.
ATM IHC | ||||
---|---|---|---|---|
MSI | ATM mutation | N | Negative | Positive |
Negative | Negative | 497 | 68 (13.7%) | 429 (86.3%) |
Positive | 24 | 4 (16.7%) | 20 (83.3%) | |
Subtotal | 521 | 72 (13.8%) | 449 (86.2%) | |
Positive | Negative | 23 | 7 (30.4%) | 16 (69.6%) |
Positive | 52 | 33 (63.5%) | 19 (36.5%) | |
Subtotal | 75 | 40 (53.3%) | 35 (46.7%) | |
Negative | 520 | 75 (14.4%) | 445 (85.6%) | |
Positive | 76 | 37 (48.7%) | 39 (51.3%) | |
Total | 596 | 112 (18.8%) | 484 (81.2%) |