Table 1.
Comparison of T1 and T2 Relaxation Times for Skeletal Muscle Metabolites at 3 T and 7 T
| Comparison of T1 Relaxation Times in Tibialis Muscle (TA) at 3 T and 7 T
| |||||||||
|---|---|---|---|---|---|---|---|---|---|
| TA | IMCL-CH3 (0.9 ppm) | EMCL-CH3 (1.1 ppm) | IMCL-CH2 (1.27 ppm) | EMCL-CH2 (1.5 ppm) | = =CH-CH2-(CH2)n (2.24 ppm) | -CO-CH2-CH= = (2.4 ppm) | Cr-CH3 (3.03 ppm) | TMA (3.2ppm) | -CH= =CH- (5.4 ppm) |
| 3 T (ms) | 866 ± 216 | 440 ± 108 | 546 ± 115 | 372 ± 119 | NM* | NM | 900 ± 147 | 1095 ± 268 | NM |
| 7 T (ms) | 1946 ± 606 | 1427 ± 338 | 1494 ± 158 | 2187 ± 1001 | 1372 ± 239 | 1971 ± 235 | 1632 ± 164 | 1339 ± 40 | 2036 ± 404 |
| Change (%) | 125 | 224 | 174 | 488 | NM | NM | 81 | 22 | NM |
|
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| Comparison of T2 Relaxation Times in Tibialis Muscle (TA) at 3 T and 7 T | |||||||||
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| |||||||||
| TA | IMCL-CH3 (0.9 ppm) | EMCL-CH3 (1.1 ppm) | IMCL-CH2 (1.27ppm) | EMCL-CH2 (1.5 ppm) | = =CH-CH2-(CH2)n (2.24 ppm) | -CO-CH2-CH= = (2.4 ppm) | Cr-CH3 (3.03 ppm) | TMA (3.2 ppm) | -CH= =CH- (5.4 ppm) |
| 3 T (ms) | 68 ± 6 | 64 ± 16 | 75 ± 5 | 81 ± 3 | NM | NM | 131 ± 14 | 110 ± 19 | NM |
| 7 T (ms) | 42 ± 12 | 53 ± 1 | 56 ± 4 | 64 ± 7 | 28 ± 7 | 29 ± 8 | 53 ± 6 | 39 ± 3 | 56 ± 21 |
| Change (%) | 38 | 17 | 25 | 21 | NM | NM | 60 | 65 | NM |
The peaks at 2.24 ppm, 2.4 ppm, and 5.4 ppm were not measurable (NM) at 3 T but could be resolved and measured at 7 T. At 7 T, T1 values increase and T2 values decrease compared with 3 T.
IMCL, intramyocellular lipid; EMCL, extramyocellular lipid; NM, not measurable.
From Wang et al.28