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Interaction of amino acids (100 μmol mL−1) with doxorubicin (8; 16; 32; 62; 125; 250; 500; 1000 μg mL−1) monitored with IELC. DOX interaction with: (J) serine; (K) aspartic acid; (L) valine; (M) glutamic acid; (N) isoleucine; (O) leucine; (P) arginine. ▴ Expression of retention time changes (min); × real curve of a sample and—calculated overlay expressing amino acids breaking points.
