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Effects of various pharmacological substances on the Zn-induced death of GT1–7 cells. (A) GT1–7 cells were exposed to 50 μM of Zn2+ with agonists or antagonists of neurotransmitters [glutamate, d-APV (d-2-amino-5-phosphonovalerate), CNQX (6-cyano-7-nitroquinoxaline-2,3-dione), muscimol, baclofen, bicuculline], GABA channel blockers [TTX (tetrodotoxin), nimodipine], etc. (B) The relative viability of GT1–7 cells exposed to Zn2+ with or without Ca2+.
