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Effects of carnosine and His on Zn-induced gene expression. GT1–7 cells were exposed to 50 μM of ZnCl2 for 6 h in the presence or absence of Ca-EDTA (0.5 mM), His (1.0 mM), or carnosine (2.0 mM). The expression of various genes were analyzed by RT-PCR and the gene expression levels were normalized against β-actin. The data are expressed as means ± S.E.M., n = 3. * p < 0.01 vs. Zn.
