Hyperoside promotes cell viability and attenuates the effects of advanced glycation end products (AGEs). Cells were seeded in 96-well culture plates. After incubation at 37 °C for 24 h, the medium was replaced with fresh medium supplemented either with or without hyperoside (50 μg/mL). After incubation for a further hour, AGEs (200 μg/mL) were added to the cells for 10 min. The viability of ECV304 cells were detected after 24 h treatment with AGEs, either in the absence or presence of hyperoside. The results are shown as a percentage of negative control. (a) AGEs vs. NC (p < 0.01); (b) AGEs + H vs. AGEs (p < 0.05). NC, negative control; H, hyperoside.