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Editing-dependent effects of ADARs on miRNA pathway. miRNA precursors (pri- and pre-miRs) undergo specific A-to-I RNA editing that (i) may block their maturation process at either Drosha or Dicer step; (ii) may affect the loading of the edited miRNA to the RISC complex; (iii) may redirect the edited miRNA to a new set of target mRNAs.
