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. 2013 Nov 20;14(11):22906–22932. doi: 10.3390/ijms141122906

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© 2013 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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PTB RRM3 structure. (A) The PTB RRM3 structure was obtained with Swiss-PdbViewer (http://www.expasy.org/spdbv/); (B) Alignments of ribonucleoprotein (RNP) 2 and RNP1 sequences present in the PTB RRM3 with RRM containing proteins. The alignment was generated by ClustalW and manually optimized. PTB, polypryrimidine tract binding protein; nPTB, neuronal PTB; hnRNPA1, heterogeneous nuclear ribonucleoprotein type A1; LA, La protein; TAP, mRNA export factor Tap; PABP, Poly(A)-binding protein; CSTF64, cleavage stimulation factor 64; Y14, Y14 Magoh complex; HUD, Hu protein; SXL, Sex-Lethal; U1A, U2B, U1 snRNP proteins; CBP20, cap-binding protein 20; UPF3, up-frameshift protein 3; U2AF65, U2 snRNP auxiliary factor; RBM20, RNA binding motif 20.