Figure 5.

Gene and miRNA interaction sub-network describing vessel specificity. Triangles represent miRNAs; circles represent mRNAs. Gene expression in the ascending aorta according to log₂ (gene expression/average gene expression) is represented by color; green indicates down-regulation, red indicates up-regulation. Under each node, histograms representing log₂ (gene expression/average gene expression) in the ascending aorta, descending aorta, inferior vena cava, and superior vena cava (reading from left to right) are shown. The area highlighted by the circle indicates the densely connected portion of the sub-network (an enlarged view of this area is available in Figure 6).