Table 3.
Multivariate logistic regression adjusted odds ratios for respiratory conditions for selected CD14 polymorphisms and haplotypes.
| Models | Asthma (n = 533) | Atopy (n = 499) | Croup (n = 533) | |||
|---|---|---|---|---|---|---|
| OR (95% CI)# | OR (95% CI)# | OR (95% CI)# | ||||
| Genotypes model | ||||||
| CD14 C-159T | ||||||
| C/C | 1.00 | 1.00 | 1.00 | |||
| C/T | 1.20 (0.68, 2.11) | 0.97 (0.55, 1.72) | 3.79 (1.13, 12.74) | |||
| T/T | 1.37 (0.61, 3.06) | 1.40 (0.67, 2.94) | 3.77 (0.89, 16.03) | |||
| CD14 G-1359T | ||||||
| G/G | 1.00 | 1.00 | 1.00 | |||
| G/T | 1.65 (0.97, 2.80) | 0.86 (0.51, 1.45) | 0.98 (0.43, 2.25) | |||
| T/T | 2.55 (1.05, 6.19) | 1.63 (0.67, 3.97) | 1.71 (0.31, 9.52) | |||
| Haplotypes model | ||||||
| C|G | 1.00 | 1.00 | 1.00 | |||
| C|T | 1.36 (0.88, 2.10) | 1.16 (0.77, 1.75) | $ | |||
| T|G | 1.04 (0.69, 1.57) | 1.21 (0.82, 1.79) | $ | |||
| T|T | 7.17 (1.49, 34.40) | 0.73 (0.08, 6.39) | $ | |||
#Adjusted for age, sex, ETS, and farming exposure. OR: odds ratio; CI: confidence interval. $Not reported due to zero counts in the cell of T|T with croup (see Table 2). Significance results are bold.