. Author manuscript; available in PMC: 2013 Dec 8.

Published in final edited form as: Nat Rev Neurol. 2011 Feb 8;7(3):10.1038/nrneurol.2011.3. doi: 10.1038/nrneurol.2011.3

Table 1.

Abnormal white matter tract connections and associated cognitive deficits in TLE

Tracts	Connections	Cognitive deficits in TLE
Arcuate fasciculus	Connects perisylvian frontal, parietal and temporal cortex	Confrontational naming¹³¹
Inferior longitudinal fasciculus	Connecting temporal lobe to the occipital lobe	Delayed memory ¹¹⁵
Inferior fronto-occipital fasciculus	Connecting frontal lobe to occipital lobe	Delayed memory ¹³¹
Uncinate fasciculus	Connections between the mesial temporal structures (uncus and amygdala) and mesial frontal region.	Immediate memory, delayed memory and confrontational naming^{115, 131, 132}

Parahippocampal cingulum	Connects the uncus and parahippocampal gyrus to subrostral areas of the frontal region	Delayed memory ¹³¹
Fornix	Connects hippocampus to other limbic regions	Immediate memory ¹¹⁵
Corpus callosum	Major connection between the two hemispheres	Psychomotor speed and executive function¹³³