Figure 2.

Patients with metastatic NB display higher levels of chromogranin and lower levels of sHLA-E than those with localized NB. Concentrations of sHLA-E (a), sHLA-F (b), chromogranin (c), and calprotectin (d) were analyzed in samples from patients with localized (white dots) or metastatic NB (black dots). Results are expressed as arbitrary units/mL for sHLA-E and sHLA-F, pg/mL for chromogranin and ng/mL for calprotectin. Horizontal bars indicated medians. P values are indicated where the difference is statistically significant.