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. 2013 Nov 21;35(6):773–790. doi: 10.1155/2013/974358

Table 1.

Biomarkers of oxidative stress.

Type of biomarker Location Reference
Ferric reducing ability of plasma Extracellular Benzie and Strain, 1996 [96]
Carbonyls Extracellular Mohanty et al., 2010 [98]
Lipid peroxidation
 Malondialdehyde Extracellular Ohkawa et al., 1979 [77]
 F2-isoprostane Extracellular Collins et al., 1999 [202]
 4-Hydroxynonenal Extracellular Halliwell and Gutteridge, 2007 [89]
Plasma vitamins
 Vitamin C Extracellular Roe and Kuether, 1943 [94]
 Vitamin E Extracellular Teissier 1996 [93]
Antioxidant enzymes
 Superoxide dismutase Intracellular Misra and Fridovich, 1972 [100]
 Catalase Intracellular Aebi and Bergmeyer, 1974 [101]
 Glutathione peroxidase Intracellular Flohé and Günzler, 1984 [102]
 GSH/GSSG ratio in erythrocyte Intracellular Hissin and Hilf, 1976 [104]
Prooxidant enzymes
 Xanthine oxidase Intracellular Haining and Legan 1967 [106]
 NADPH oxidase Intracellular Nauseef, 2008 [17, 18]
Others
 Endothelial microparticles Extracellular Burger and Touyz, 2012 [109]
 Endothelial progenitor cells Extracellular Touyz and Schiffrin, 2012 [111]
 Ischemia modified albumin Extracellular Sinha et al., 2003 [194]