. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: Prev Med. 2013 Sep 9;57(5):10.1016/j.ypmed.2013.08.032. doi: 10.1016/j.ypmed.2013.08.032

Table 5.

Positive predictive value of three different FOBTs, Group Health, Washington State 2010-2012^a

	OC-Auto®	InSure®	Hemoccult SENSA®
FOBT positive, No.	16	21	14
Followed-up by colonoscopy, No.	12	21	14
High-risk finding per modified USMSTF guidelines^a
No.	4	5	4
PPV (95% confidence interval)	33% (10%-65%)	24% (8%-47%)	29% (8%-58%)
High-risk finding per adapted USMSTF guidelines^a, excluding sessile adenomas removed piecemeal
No.	2	5	2
PPV (95% confidence interval)	17% (2%-48%)	24% (8%-47%)	14% (2%-42%)
Any adenoma or cancer^b
No.	7	8	7
PPV (95% confidence interval)	58% (28%-85%)	38% (18%-62%)	50% (23%-77%)

Abbreviations: FOBT, fecal occult blood test; PPV: positive predictive value; USMSTF: United States Multi-Society Task Force.

USMSTF defines high risk as cancer, ≥3 adenomas, adenoma >1 cm (we used ≥1 cm), adenoma with villous features, adenoma with high-grade dysplasia, or sessile adenomas removed piecemeal.

All were adenomas. PPVs were computed based on test returned rather than randomization group. Three of the participants assigned to the OC-Auto FIT test had completed a standard Group Health gFOBT instead of the study FIT.