Skip to main content
. Author manuscript; available in PMC: 2013 Dec 8.
Published in final edited form as: J Nucl Med. 2011 Jun 16;52(7):10.2967/jnumed.110.084525. doi: 10.2967/jnumed.110.084525

FIGURE 5.

FIGURE 5

Dopamine transporter occupancy vs. plasma level. Percentage occupancy of dopamine transporter as measured with 11C-PE2I PET images is plotted. Curve was fit to data using a nonlinear least-squares method. Parameters for best-fit curve were maximum occupancy of 84.9% and 4.5 ng/mL drug plasma concentration at 50% occupancy. These parameters are indicated in equation of fitted curve shown on top left corner. For 1 subject (S034), 27-h plasma level was used, because this subject received 11C-PE2I scan at approximately 27 h after dose administration. DAT = dopamine transporter.