Table 1.
Comparison of leading mass spectrometers for lipidomics
| Resolution | Mass range(m/z) | Mass accuracy(ppm) | |
| ToF | 2-5 typical | ||
| Waters LCT premier | 10000 | 18000 | NA |
| Agilent LC/ToF | > 22000 | 50-20000 | < 1 |
| Bruker microToF | 10000 | 3000 | NA |
| QToF | Same as ToF | ||
| Agilent 6540 | > 40000 | 50-10000 | < 1 |
| Waters QToF ultima | 17500 | 32000 | 1 |
| Waters QToF micro | 5000 | 20000 | 1 |
| Bruker max is 4G | > 60000 | 10000 | < 1 |
| LTQ velos | 3000 | 4000 | 0.1 Da |
| LTQ-orbitrap velos | > 100000 | 4000 | < 2 |
| TSQ quantum access max | 0.4 (FWHM) | 3000 | 0.1 Da |
| TSQ quantiva | 0.2 (FWHM) | 1850 | 0.1 Da |
| Q-exactive | 140000 | 6000 | < 1 |
| Orbitrap fusion tribrid | 450000 | 4000 | < 1 |
| Synapt G2-HDMS | 40000 | 32000 (1000001) | < 1 |
| Synapt G2S-HDMS | 20000 | 32000 (1000001) | Approx- imately 2 |
1
When fitted with a quadrupole. m/z: Mass to charge ratio, ppm: Parts per million; LCT: Liquid chromatograph; LTQ: Linear trap quadropole; TSQ: Triple stage quadrupole; HDMS: High definition mass spectrometry; FWHM: Full width at half maximum; ToF: Time of flight; NA: Not available.