Table 3.

Estimated Mean Change in Body Mass Index, Weight Change, Percent Weight Change over a 15-Month Period in the Intention-to-Treat Population^*

Outcome Variable	Usual Care (n=81)	Coach-led (n=79)	Self-directed (n=81)	P value
				Coach-led vs. Usual Care	Self-directed vs. Usual Care	Coach-led vs. Self-directed
BMI (kg/m2)
Baseline	32.0 ± 5.4	32.4 ± 6.3	31.8 ± 5.1	N/A	N/A	N/A
At month 3	31.5 ± 0.3	29.9 ± 0.2	30.2 ± 0.3	<0.001	<0.001	0.07
At month 6	31.5 ± 0.3	29.4 ± 0.3	30.2 ± 0.3	<0.001	<0.001	<0.001
At month 15	30.9 ± 0.3	29.6 ± 0.3	30.2 ± 0.3	<0.001†	0.02†	0.03
Change in BMI (kg/m2)
At month 3	−0.3 ± 0.3	−1.9 ± 0.3	−1.6 ± 0.3	<0.001	<0.001	0.07
At month 6	−0.3 ± 0.3	−2.4 ± 0.3	−1.5 ± 0.3	<0.001	<0.001	<0.001
At month 15	−0.9 ± 0.3	−2.2 ± 0.3	−1.6 ± 0.3	<0.001	0.02	0.03
Weight Change (kg)
At month 3	−0.7 ± 0.8	−5.4 ± 0.7	−4.5 ± 0.8	<0.001	<0.001	0.09
At month 6	−0.7 ± 0.9	−6.6 ± 0.8	−4.3 ± 0.8	<0.001	<0.001	<0.001
At month 15	−2.4 ± 0.9	−6.3 ± 0.9	−4.5 ± 0.9	<0.001	0.02	0.04
Percent Weight Change
At month 3	−0.7 ± 0.8	−5.8 ± 0.8	−4.9 ± 0.8	<0.001	<0.001	0.09
At month 6	−0.9 ± 0.9	−7.2 ± 0.9	−4.7 ± 0.9	<0.001	<0.001	0.001
At month 15	−2.6 ± 0.9	−6.6 ± 0.9	−5.0 ± 0.9	<0.001	0.008	0.07

^*Plus-minus values are means ± SE. The data for the three study groups are covariate-adjusted, mixed model-based estimates for the intention-to-treat population.

^†The primary comparisons between the two active interventions and usual care remain statistically significant (P<0.05) after the Bonferroni correction was applied by multiplying the calculated P values by a factor of 2.