Table 4.
Older age associated with reduced functional connectivity between the left and right caudate and the left and right VLPFC during Updating (UPD beta series analysis)
| Seed | Region | # of voxels |
Peak Z score |
p value | Corrected p value |
x | y | z |
|---|---|---|---|---|---|---|---|---|
| Caudate - L | VLPFC - L | 44 | 3.36 | 0.000 | 0.007 | −24 | 12 | −18 |
| VLPFC - R | 115 | 4.87 | 0.000 | 0.000 | 21 | 15 | −18 | |
| Caudate - L | 64 | 3.84 | 0.000 | 0.034 | −12 | 18 | 3 | |
| Caudate - R | 57 | 3.49 | 0.000 | 0.034 | 15 | 12 | 12 | |
| Caudate - R | VLPFC - L | 16 | 2.83 | 0.002 | 0.051 | −21 | 9 | −18 |
| VLPFC - R | 45 | 4.08 | 0.000 | 0.005 | 21 | 15 | −18 | |
| VLPFC - L | Caudate - L | 16 | 2.77 | 0.003 | 0.065 | −12 | 9 | 6 |
| Caudate - R | 28 | 3.31 | 0.000 | 0.059 | 18 | 9 | 12 | |
| VLPFC - R | Caudate - L | 31 | 3.76 | 0.000 | 0.004 | −12 | 12 | 3 |
| Caudate - R | 49 | 4.33 | 0.000 | 0.004 | 15 | 12 | 15 | |
| VLPFC - R | 45 | 4.17 | 0.000 | 0.012 | 21 | 21 | −21 |
ROI analyses using WFU PICKATLAS tool