. Author manuscript; available in PMC: 2013 Dec 9.

Published in final edited form as: J Thromb Haemost. 2010 Sep;8(9):10.1111/j.1538-7836.2010.03927.x. doi: 10.1111/j.1538-7836.2010.03927.x

Table 4.

Association of c.2771 genotype with median levels of VWF and FVIII:C in EU healthy controls

c.2771G>A genotype & ABO blood group	FVIII:C			VWF:Ag			VWF:RCo			FVIII:C/VWF:Ag
c.2771G>A genotype & ABO blood group	n	IU/dL	p	n	IU/dL	p	n	IU/dL	p	n	ratio	p
All
GG	1064	109	^‡	1070	98	NS	1063	95	NS	1063	1.14	^*
GA	35	88	^‡	35	87	NS	35	85	NS	35	1.09	^*
O
GG	395	98	^†	399	81	^*	395	82	NS	395	1.18	NS
GA	13	78	^†	13	70	^*	13	67	NS	13	1.20	NS
Non-O
GG	648	118	^‡	650	108	NS	647	103	NS	647	1.12	^*
GA	21	93	^‡	21	94	NS	21	111	NS	21	0.96	^*

The number of subjects in the “All” group is larger than those included in the other two groups due to inclusion of HC with undetermined blood groups.

indicate degree of significance between GG and GA subjects (p<0.05, p<0.01 and p<0.0001, Mann-Whitney test); NS indicates nonsignificant differences

^†

indicate degree of significance between GG and GA subjects (p<0.05, p<0.01 and p<0.0001, Mann-Whitney test); NS indicates nonsignificant differences

^‡

indicate degree of significance between GG and GA subjects (p<0.05, p<0.01 and p<0.0001, Mann-Whitney test); NS indicates nonsignificant differences