FIGURE 1.

Thin-layer radiochromatographic profile of methanolic fecal extracts following both intravenous (iv) and oral administration of ¹⁴C-sucralose: (a) 0–24 h fecal sample from a male rat given an iv dose of ¹⁴C-sucralose (2 mg/kg); (b) 0–24 h fecal sample from a male rat maintained on a diet containing 30,000 ppm sucralose for 85 wk before receiving an oral dose of ¹⁴C-sucralose (100 mg/kg). An enlargement of the peak profile is given to the right. (TLC traces from Sims et al., 2000).