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. 2013 Oct 8;13:463. doi: 10.1186/1471-2407-13-463

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Copyright © 2013 Cross-Knorr et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Phosphorylated RKIP in stage II colon cancer is associated with poor prognosis. (A) Representative examples of immunohistochemical staining for pRKIP showing strongly positive (3+) and negative levels. (B) Kaplan-Meier plot comparing the recurrence-free survival of patients with high versus low levels of nuclear pRKIP. Patients with lower levels experienced significantly longer recurrence-free survival (p = 0.0268). Bar is 100 micron. (C) Graphic representation of the correlation between lymphovascular invasion and pRKIP levels (p = 0.03).