Table 3.
Parameters | 3D-CRT | IMRT | VMAT | 3D-CRT vs IMRT | IMRT vs VMAT | 3D-CRT vs VMAT |
Lung ipsilateral | ||||||
Dmean (Gy) | 12.097±3.00 | 12.097±3.00 | 12.097±3.00 | 0.320 | <0.0001 (****) | <0.0001 (****) |
V5 (%) | 40.710±11.71 | 68.317±19.56 | 94.241±5.63 | <0.0001 (****) | 0.0002 (***) | <0.0001 (****) |
V10 (%) | 28.369±6.96 | 43.461±13.88 | 70.222±9.91 | 0.0001 (***) | <0.0001 (****) | <0.0001 (****) |
V20 (%) | 22.486±5.61 | 19.908±3.45 | 29.181±9.00 | 0.072 | 0.003 (**) | 0.008 (**) |
V30 (%) | 19.485±5.25 | 12.965±1.70 | 14.417±4.18 | 0.0004 (***) | 0.251 | 0.001 (**) |
V40 (%) | 14.637±6.59 | 5.748±1.63 | 6.246±2.42 | 0.0003 (***) | 0.544 | 0.0003 (***) |
Lung contralateral | ||||||
Dmean (Gy) | 0.692±1.23 | 0.692±1.23 | 0.692±1.23 | 0.018 (*) | 0.023 (*) | 0.008 (**) |
V2 (%) | 0.685±1.05 | 22.960±27.06 | 81.762±19.60 | 0.014 (*) | <0.0001 (****) | <0.0001 (****) |
V5 (%) | 0.001±0.003 | 5.318±9.57 | 19.512±12.88 | 0.081 | 0.005 (**) | 0.0003 (***) |
V10 (%) | 0.000±0.00 | 0.893±1.66 | 0.962±1.278 | 0.09 | 0.87 | 0.024 (*) |
3D, three dimensional; CRT, conformal radiotherapy; Dmean, mean dose; IMRT, intensity-modulated radiotherapy; V10, volume receiving 10 Gy; V2, volume receiving 2 Gy; V20, volume receiving 20 Gy; V30, volume receiving 30 Gy; V40, volume receiving 40 Gy; V5, volume receiving 5 Gy; VMAT, volumetric modulated arc therapy.