Table 5.
Parameter for left-sided breast cancer cases, including PTV coverage, VMAT, age and dose to the lungs and heart
| Parameters | 3D-CRT | IMRT | VMAT | 3D-CRT vs IMRT | IMRT vs VMAT | 3D-CRT vs VMAT |
| PTV | ||||||
| V95% | 93.479±2.25% | 94.213±2.76% | 89.732±3.15% | 0.704 | 0.011 | 0.094 |
| D95 (Gy) | 45.689±3.68 (91.378%) | 47.197±0.88 (94.394%) | 46.289±0.71 (92.578%) | 0.382 | 0.02 (<0.05) | 0.705 |
| Lung—left | ||||||
| V40 | 13.142%±7.76 | 7.699%±2.12 | 7.126%±2025 | 0.09 | 0.661 | 0.116 |
| V20 | 21.905%±4.97 | 19.812%±2.67 | 25.06%±4.50 | 0.168 | 0.055 | 0.274 |
| V5 | 34.343%±6.34 | 60.420%±11.75 | 93.395%±4.24 | 0.002 (<0.01) | 0.0008 (<0.001) | <0.0001 (<0.0001) |
| Dmean (Gy) | 11.243±2.53 | 12.297±1.64 | 16.293±0.96 | 0.178 | 0.0096 (<0.01) | 0.009 (<0.01) |
| Lung—right | ||||||
| V5% | 0.000%±0.00 | 0.148%±0.3 | 14.796%±12.29 | 9.276 | 0.031 (<0.05) | 0.032 (<0.05) |
| Dmean (Gy) | 0.153±0.06 | 0.697±0.19 | 5.592±5.94 | 0.002 (<0.01) | 0.1 | 0.076 |
| Heart | ||||||
| V40 | 6.548%±3.85 | 1.988%±0.60 | 2.330%±1.50 | 0.02 (<0.05) | 0.0533 | 0.016 |
| V20 | 11.657%±2.50 | 12.779%±3.54 | 15.369%±6.14 | 0.232 | 0.249 | 0.126 |
| V5 | 18.568%±3.44 | 46.675%±13.01 | 85.921%±15.92 | 0.003 (<0.01) | 0.002 (<0.01) | 0.0001 (<0.001) |
| D5 (Gy) | 43.489±4.16 | 33.475±3.78 | 33.396±4.82 | 0.0004 (<0.001) | 0.970 | 0.001 (<0.01) |
| Dmean (Gy) | 6.557±1.24 | 8.782±1.49 | 12.412±2.47 | 0.004 (<0.01) | 0.015 (<0.05) | 0.001 (<0.01) |
3D, three dimensional; CRT, conformal radiotherapy; D95, the dose distributed in ≥95% of the PTV; Dmean, mean dose; IMRT, intensity-modulated radiotherapy; PTV, planning target volume; V20, volume receiving 20 Gy; V40, volume receiving 40 Gy; V5, volume receiving 5 Gy; V95%, volume receiving 95% of the prescribed dose; VMAT, volumetric modulated arc therapy.