Table 4.
Summary of Histopathology Findings
| Group 1, BSS control | |
| Pancreas | |
| Granuloma, mild | ++ (1) |
| Group 2, 4×108 vg | |
| Kidney | |
| Ectasia, tubular | + (1), ++ (3) |
| Skeletal muscle, diaphragm | |
| Infiltration, mononuclear cell | + (2) |
| Skeletal muscle, quadriceps | |
| Infiltration, mononuclear cell | + (2) |
| Pancreas | |
| Infiltration, mononuclear cell | + (1) |
| Group 3, 4×109 vg | |
| Kidney | |
| Ectasia, tubular | + (2), ++ (1) |
| Skeletal muscle, quadricep | |
| Infiltration, mononuclear cell | + (2) |
| Lung | |
| Accumulation, macrophage | + (1) |
| Pancreas | |
| Granuloma | + (1) |
+, minimal; ++, mild; +++, moderate; ++++, marked. The number of subjects is shown in parentheses.
BSS, balanced salt solution; vg, vector genomes.