Table 2.
Large sequence polymorphisms present in M. bovis field isolates
| Mb CDS | Mtb CDS | Genomic postn. (wrt to 2122/97) | Size of deletion (bp) | Gene(s) | 2122/97 | 1121/01 | 2451/01 | 1307/01 | Product(s) |
|---|---|---|---|---|---|---|---|---|---|
| Mb1699c |
Rv1627c |
n/d |
n/d |
|
|
|
|
DEL |
Probable lipid transfer protein |
|
aMb1963c-Mb1971 |
Rv1928c-Rv1936 |
2172231-2179038 |
6807 |
tpx, fadE17, fadE18, echA13 |
|
DEL |
|
|
Gene products have roles in lipid metabolism |
| Mb2054c |
Rv2029c |
2259798-2261457 |
1659 |
pfkB |
|
|
|
DEL |
Possible phosphofructokinase |
| Mb2055c/Mb2056c |
Rv2030c |
|
|
|
|
|
|
DEL |
Conserved hypothetical protein (frame-shifted in 2212/97) |
| Mb2320 |
Rv2298 |
n/d |
n/d |
|
DEL |
DEL |
|
|
Aldo/keto reductase |
| Mb3923c | Rv3894c | n/d | n/d | DEL | Conserved membrane protein (frame-shifted in 2212/97) |
DEL indicates genes that are deleted from strains.
aMostowy et al., 2005; n/d, not determined.