Table 2.
The RAD50 _rs17166050 genotypes/allele frequency distribution and logistic regression analysis (with odds ratio and 95% confidence interval) in laryngeal cancer (LC), multiple primary tumors with laryngeal cancer (MPT-LC), multiple primary tumors of head and neck (MPT) and controls
| Genotype/allele |
Controls n (%) |
LC n (%) |
OR (95% CI) |
MPT-LC n (%) |
OR (95% CI) |
MPT n (%) |
OR (95% CI) |
|---|---|---|---|---|---|---|---|
| GG |
233 (47) |
87 (50) |
1* |
50 (44) |
1* |
24 (35) |
1* |
| GA |
195 (40) |
69 (39) |
1.06 (0.74-1.53) |
57 (50) |
0.73 (0.48-1.12) |
38 (56) |
0.53 (0.31-0.92)† |
| AA |
66 (13) |
19 (11) |
1.30 (0.74-2.29) |
8 (6) |
1.78 (0.80-3.92) |
6 (9) |
1.13 (0.44-2.89) |
| GA+AA |
261 (52) |
88 (50) |
1.11 (0.78-1.56) |
65 (57) |
0.86 (0.57-1.30) |
44 (65) |
0.61 (0.36-1.04) |
| G |
661 (66) |
243 (69) |
1* |
157 (68) |
1* |
86 (63) |
1* 0.85 |
| A | 327 (34) | 107 (31) | 1.12 (0.87-1.46) | 73 (22) | 1.06 (0.78-1.45) | 50 (37) | (0.59-1.24) |
*Reference category; OR (95% CI) – odds ratio (95% confidence interval); † Result statistically significant (p=0.0205).