Table 3B.
Haplotype association tests
| Population | Gene | SNPs | Haplotype | P | 
|---|---|---|---|---|
| Caucasian | DRD2 | rs6277/rs1076560/rs2283265 | ACC | 0.0002 | 
| DRD2 | rs6277/rs1076560/rs2283265 | GAA | 0.02 | |
| DRD2 | rs6277/rs1076560/rs2283265 | GCC | 0.05 | |
| 
 | ||||
| African-American | N/A | |||
| 
 | ||||
| Hispanic | N/A | |||
Abbreviations: SUD, substance dependence; DRD1, dopamine D1 receptor; DRD2, dopamine D2 receptor; SNP, single nucleotide polymorphism. SNP in BOLD remains significant after Bonferroni correction for multiple comparisons. Hispanic population comprises a subset of the Caucasian and African American samples.