Table 1.
BDd | UDd | HC | Overall significance* | Pair-wise comparisons (d.f.=18) | |
---|---|---|---|---|---|
Mean age (years) | 15.6 ± 0.9 | 15.9 ± 1.1 | 15.6 ± 1.2 | p = 0.6, F=0.4 | – |
Gender (females) | 80% | 80% | 80% | p = 0.6, F=0 | – |
Race (White) | 70% | 70% | 70% | p = 1, F=0.4 | – |
Family history of BD (%) | 90% | 0% | 0% | – | – |
BD subtypes | 5 BD I, 5 BD II | N/A | N/A | – | – |
Comorbid ADHD | 30% | 20% | 0% | p = 0.2, F=1.7 | – |
Comorbid anxiety disorders | 70% | 60% | 0% | p = 0.001, ×2 =8.6 | BDd > HC, ×2 = 10.8**UDd > HC, ×2 = 8.6** |
Mean duration of the current depressive episode (weeks) | 8.1 ± 6.3 | 13.8 ± 6.2 | – | p = 0.06, F=4.2 | – |
Children's Depression Rating Scale-Revised (CDRS-R) | 74.5 ± 12.8 | 65.8 ± 13.3 | 19.1 ± 1.8 | p = 0.0001, F=78.4 | BDd > HC, t=13.7**UDd > HC, t= 11.1** |
Screen for Child Anxiety Related Emotional Disorders (SCARED) | 34.3 ± 17.8 | 28.1 ± 14.7 | 2.2 ± 1.4 | p = 0.0001, F=16.2 | BDd > HC, t=5.7**UDd > HC, t=5.5** |
Young Mania Rating Scale (YMRS) | 2.5 ± 2.1 | 2.2 ± 1.1 | 0.8 ± 0.8 | p = 0.003, F = 7.5 | BDd > HC, t=3.8**UDd > HC, t=3.2** |
Mean of the Clinical Global Impression (CGI)-Severity | 5.5 ± 0.5 | 5 ± 0.8 | 1 | p = 0.0001, F =190.2 | BDd > HC, t=26.9**UDd > HC, t=15.5** |
BDd: bipolar disorder in depressed state, UDd: unipolar major depressive disorder in depressed state, HC: healthy controls, N/A: not available, ADHD: attention deficit hyperactivity disorder.
Significance level was set at p < 0.05. Standard deviation is reported after ±. Statistical values, significance levels, and d.f. (degrees of freedom) are presented in the table. Group differences are shown in bold in the table and indicated by asterisks
for a significance level of p < 0.01.