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. Author manuscript; available in PMC: 2013 Dec 9.
Published in final edited form as: Curr Enzym Inhib. 2011 Jul;7(2):10.2174/157340811796575317. doi: 10.2174/157340811796575317

Fig. 14.

Fig. 14

a. Representation of the inhibition mechanism of eIPP against IDI-2. First epoxide is activated by protonation and then an attack of a near-by nucleophilic group of the IDI-2 active centre form covalent bond. b. IDI-2 reaction is similar to IDI-1, which proceeds via carbocation-type intermediate. The FMNH2 is acting as a nucleophilic group.