Table 3.
Association between PTP1B expression and breast cancer intrinsic subtypes
Molecular subtype | PTP1B-positive (n) | % | PTP1B-negative | % | p value |
---|---|---|---|---|---|
Luminal A (ER+ and/or PR+, HER2–, Ki-67 <14 %) | 107 | 49.1 | 111 | 50.9 | <0.008 |
Luminal B (HER2-negative) ER+ and/or PR+, HER2–, Ki-67 ≥ 14 %) | 344 | 50.4 | 339 | 49.6 | |
Luminal B (HER2-positive) (ER+ and/or PR+, HER2+) | 84 | 53.9 | 72 | 46.1 | |
HER2 type (ER– or PR–, HER2+) | 58 | 52.2 | 53 | 47.8 | |
Basal-like (ER–,PR–, HER2–) | 86 | 37.9 | 141 | 62.1 |