Table 4.
Univariate analyses for the effect of PTP1B on OS, as well as the interaction effect between PTP1B and other factors (ER and HER2 status, intrinsic subtype)
| Hazard ratio (95 % CI) | p value | |
|---|---|---|
| All cases | ||
| PTP1B ≥5 % | 0.763 (0.641–0.908) | 0.002 |
| Interaction with ER status | 0.019* | |
| ER+ | 0.693 (0.561–0.858) | 0.001 |
| ER– | 1.082 (0.797–1.468) | 0.733 |
| Interaction with HER2 status | 0.129* | |
| HER2+ | 0.972 (0.677–1.396) | 0.896 |
| HER2– | 0.706 (0.578–0.862) | <0.001 |
| Interaction with intrinsic subtype | 0.049* | |
| Luminal A | 0.568 (0.321–1.003) | 0.051 |
| Luminal B (HER2–) | 0.661 (0.510–0.856) | 0.002 |
| Luminal B (HER2+) | 0.994 (0.607–1.629) | 0.981 |
| HER2 type | 0.999 (0.586–1.705) | 0.998 |
| Basal-like | 1.107 (0.751–1.632) | 0.607 |
p values for interaction terms