Table 4.
Univariate analyses for the effect of PTP1B on OS, as well as the interaction effect between PTP1B and other factors (ER and HER2 status, intrinsic subtype)
Hazard ratio (95 % CI) | p value | |
---|---|---|
All cases | ||
PTP1B ≥5 % | 0.763 (0.641–0.908) | 0.002 |
Interaction with ER status | 0.019* | |
ER+ | 0.693 (0.561–0.858) | 0.001 |
ER– | 1.082 (0.797–1.468) | 0.733 |
Interaction with HER2 status | 0.129* | |
HER2+ | 0.972 (0.677–1.396) | 0.896 |
HER2– | 0.706 (0.578–0.862) | <0.001 |
Interaction with intrinsic subtype | 0.049* | |
Luminal A | 0.568 (0.321–1.003) | 0.051 |
Luminal B (HER2–) | 0.661 (0.510–0.856) | 0.002 |
Luminal B (HER2+) | 0.994 (0.607–1.629) | 0.981 |
HER2 type | 0.999 (0.586–1.705) | 0.998 |
Basal-like | 1.107 (0.751–1.632) | 0.607 |
p values for interaction terms